Analiza stanow podgoraczkowych jako objawu odczynu popromiennego u pacjentow napromienianych w obszarze klatki piersiowej z powodu raka pluca

Abstract

Author(s): KRZYSZTOF SZCZEPANIK, HUBERT URBANCZYK, BOZENA JOCHYMEK, JADWIGA CIECHOWICZ, LESZEK MISZCZYK

Introduction: Chest irradiation effects risk of unacceptable post-irradiative effects. There are two different kinds of those effects, acute (early) and late. Acute post radiation effect, first of all pneumonia could be the reason of breaking radiotherapy and decreasing of total dose. Acute effect should be monitored during irradiation.

Purpose: Evaluation of body temperature changing and usefulness of body temperature measurement during fractionated irradiation in lung cancer patients.

Material: The material composed of 20 lung cancer patients irradiated between December 2006 and April 2007 in Cancer Centre-Institute MSC in Gliwice. Patients were treated using dose 1.8-2.0 Gy, most often 2 Gy. There were two parts of treatment, irradiation tumour with the whole mediastinum to the dose about 44 Gy followed by conformal radiotherapy of tumour changed lymphnodes. All of the patients were treated with total dose higher than 50 Gy. Body temperatures were measured every morning and evening. Komogorow-Smirnow with Lillieforse probability, U-Manna- Whitney and Kruskal-Wallis tests were used.

Results: Median morning body temperature was 36,7 grade of centigrade and median evening temperature was 36,8 grade of centigrade. Standard deviation was 0,1358 for morning and 0,2867 for evening temperatures. We did not observe any correlation between absorbed dose and the temperature of body although standard deviation for evening temperatures were higher after dose 40 Gy than for dose less than 20 Gy (0,091 vs. 0,027).

Conclusion: Measurement of body temperature is not a good way of monitoring during lung cancer irradiation. We did not observe fever at patients in analyzed group

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