Associations of Vitamin D, Calcium, Magnesium And Phosphorus With Pre And Postmenopausal Breast Cancer Patients In Iraqi Woman

Abstract

Author(s): Nasr Afit Alobaidy, Hameed Hussein Ali, AbdulKarim-Talaq Mohammad

The objective of this study was to evaluate the association of serum vitamin D, serum Calcium, serum Phosphorus and serum Magnesium levels with Breast Cancer risk in Iraqi women. In current study, participated 100 women's, 60 women's with Breast Cancer and 40 women healthy. The status divided to two group’s pre-menopausal and post-menopausal group. Concentration of Calcium, Phosphorus and Magnesium were measured using Semi-Auto Analyzer and level of vitamin D were determined by the enzyme-linked fluorescence assay (ELFA) technique. In pre and post-menopausal patients, the mean serum vitamin D, Calcium and Magnesium levels was significantly lower than in control, while serum Phosphorus level in case was higher than in control. A negative correlation was observed between vitamin D, Calcium, Magnesium and Phosphorus with pre-menopausal patients. In post- menopausal patients was observed a negative correlation between vitamin D and Magnesium, while observed a positive correlation between Calcium and Phosphorus with breast cancer. Based on these findings, it can be concluded that vitamin D, Magnesium and Calcium deficiency and high levels of Phosphorus can be considered as risk factors for women's with breast cancer. Therefore, routine screening of these parameters in womans with Breast Cancer is recommended to reduce the incidence of disease. .

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