Childhood nutrition and adult bone tumours- A systematic review

Abstract

Author(s): R.G. Koteeswar Rao, Shah Het Shailesh Kumar, Sruthi S, M.R. Suchitra

Explaining how a childhood nutrition can influence the development of adult bone cancer is an attractive review in some aspects of public health and preventive medicine. Skeletal growth is primarily determined in formative years and nutritional deficiencies during these years raises susceptibility to bone malignancies in future. This systematic review is aimed at reviewing how deficiencies in some of the macro- and micronutrients affect the bone health in the long run as well as the risks of cancer. This systematic review examines the link between childhood nutrition and later life bone cancers, following PRISMA guidelines, utilizing databases like PubMed and Scopus, and focusing on peer-reviewed studies from 2000-2023. Some of the important nutrients include; protein, calcium and magnesium they are vital in the development of bones as well as the strength of bones. Dietary protein requirement in children affects bone mineralization and insulin-like growth Factor I IGF-I. Calcium is necessary for the development of bones and teeth and also phosphorus needed for DNA synthesis. Lack of these nutrients can make the bones to become weak and acts as a stage where diseases such as osteoporosis can be developed and this makes those affected to be at a higher risk of getting bone cancers like osteosarcoma. Also, various deficiencies including zinc, phosphorus, potassium and other vitamins and minerals affect bone formation and remodelling. These risks increase probably due to the increased intake of fast foods which have led to nutritional imbalances. Digital public health literacy interventions for improving childhood nutrition education and security have to be an all-inclusive program. Measures should also help consumers meet their needs of other essential nutrients especially in the interest-bearing regions. Proper childhood nutrition is essential for establishing strong skeletal foundations, potentially reducing the risk of bone cancers in later life. Ensuring adequate intake of vital nutrients during the formative years can significantly contribute to lifelong bone health and lower the incidence of bone malignancies. Childhood obesity and reduced fruit/vegetable intake are increasing, and nutritional awareness is low even among literates. Public awareness campaigns targeting students about proper nutrition and its role in preventing bone cancer are needed to address health issues and to better long-term outcomes.

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