Demographic and overall survival pattern of diffuse large b-cell lymphoma in the university of Calabar teaching hospital, Calabar

Abstract

Author(s): Kingsley Akaba*, Edak Akaba and Eyam S Eyam

Background: In Diffuse Large B-cell Lymphoma is an aggressive heterogeneous form of Non-Hodgkin’s lymphoma. There is dreath of information in the demographics and overall survival in low resource setting. The aim of this study is to determine the demography and overall survival pattern of Adult DLBCL at the University of Calabar Teaching Hospital. Method: The study is a retrospective study of 7 DLBCL patients seen and managed at the UCTH from June 2017 to August 2021. Male/female distribution was 2.5/1, with a median age of 62 years. Overall Survival (OS) and Progression Free Survival (PFS) were determined using the Kaplan-Meier techniques. The data were analysed using Microsoft Excel 2016 and IBM SPSS version 21. Results: Total of 7 DLBCL patients were seen over the 5-year-period of review median age 62 years. There were 5 males and 2 females. This study also shows an overall survival of 48 months with a median survival of 6.5 months. The survival distributions were not statistically significantly different, X2=3.204, p=0.073. Conclusion: There is inconsistency in the demographic and overall survival pattern of Diffuse large B Cell lymphoma in our environment. Further study is needed to identify the factors which can help to improve the overall survival pattern in our environment.

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