Emerging biomarkers in cancer diagnosis and prognosis: Novel approaches for precision oncology

Abstract

Author(s): Priyanka Verma, Namita A. Raytekar, Maher Ali Rusho, Priyadarshini, Anupama Shetter, Rohan Shinkre

Background: This study analysed the emerging biomarkers in cancer prognosis and diagnosis, with a special focus on novel approaches for precision oncology. The incorporation of cancer biomarkers in oncology has significantly transformed cancer treatment by developing remarkable advancements within cancer therapeutics. Novel biomarker helps in utilising biological samples, for instance, urine, blood and tissue biopsies for the identification of proteins, metabolites and nucleic acids. This approach guides the use of spatial and temporal variables for gene expression to understand cellular proliferation and angiogenesis by reflecting different degrees of signals. Methodology: This study has used secondary sources to collect relevant qualitative information to offer sound conclusions. In order to illustrate the collected data, content analysis has been used here. Lastly, this study has maintained proper reliability & validity while conducting the research. Results: It has been found from the study that the accessibility of a high throughput process for the determination of transformed cellular molecules permits the use of biomarkers for cancer diagnosis. Conclusion: In conclusion, precision oncology is generally dependent on the high-throughput significant molecular profiling of cancer cells which permits the determination of genomic modifications through the use of biomarkers.

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