Energy metabolism therapy for Brain Cancer

Abstract

Author(s): Tejasvi* and Amit Nayak

Brain tumours that are malignant are a serious health issue that can affect both children and adults and are frequently difficult to treat. In any case, late examination recommends that adjustments of metabolic climate could be a promising arrangement. It may be possible to manage brain cancer more effectively by combining metabolic control analysis with the capacity of normal cells to survive extreme changes in the physiological environment. By switching the bioenergetics source from glucose to ketone bodies, this strategy targets brain tumours through integrated anti-inflammatory, anti-angiogenic, and pro-apoptotic mechanisms. Both orthotropic mouse brain tumour models and human paediatric astrocytomas treated with dietary energy restriction and the ketogenic diet have successfully tested this strategy.

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