Enhancing oncology and radiotherapy practice: The advantages of propofol and fentanyl in curettage procedures

Abstract

Author(s): Ahmed Sabah Mohammed Jamil*, Hayder Hamza Alabedi and Imad Khalid Ahmed

Propofol and fentanyl have broadly used alone or in combination to induce sedation or anesthesia. The current study aims to assess the additive impact and economic benefit of using combination of propofol and fentanyl in elective curettage cases in Iraq. A total of 75 women were recruited to perform clinical trial between 1st January and 10th March 2023 at the department of gynecology and obstetrics in the Baghdad teaching hospital, Iraq. The sample was subdivided equally into three groups and received different doses of propofol alone (GI), Fentanyl alone (GII), and combination of propofol and fentanyl (GIII) respectively. The dose required for propofol to induce general anesthesia declined to 1.4 mg/kg -1.5 mg/kg instead of 2.5mg/kg, and 2 µg/kg instead of 8 µg/kg for fentanyl in the combination. Out of 25 cases, 19 (76%) patients being unconscious in a time of two minutes as a result of additive effect. Moreover, the cost evaluation showed a cost saving of USD 0.09/minute for every operated curettage weighing 65kg and average surgical time of 21.57+11.06 minutes. The combination of propofol and fentanyl is effective for sedation and anesthesia and cost saving.

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