Epidemiological evolution of colorectal cancer in 10 years: Incidence, mortality and survival: Experience of the medical oncology department of Fez

Abstract

Author(s): Soukaina El Anssari*, Youssef Elhaitmy, Lamiae Amaadour, Karima Oualla, Zineb Benbrahim, Samia Arifi and Nawfel Mellas

Colorectal cancer is the second digestive cancer in Morocco after gastric cancer and ranks second among malignancies in terms of incidence and mortality in rich countries. The aim of this study was to report trends in the incidence and presentation of Colorectal Cancer (CRC) over a 10-years period. This is a retrospective study which included 664 patients with colon cancer treated at the medical oncology department of Fez over a period from December 2010 to August 2020. Kaplan Meier method was used to evaluate median survival. The incidence of CRC increased from 48 cases /year to 85 cases /year in 2010 and 2020 respectively. 140 cases were recorded between 2008-2010 versus 190 cases between 2018-2020. We observed a rejuvenation of colorectal cancer with an age ranging from 75 years in 2010 to 65 years in 2020. Sex ratio was 1.6 in 2010 versus 1.2 in 2020. Diagnosis at an early stage of the disease has considerably increased in recent years. We reported non-significant variations in tumour localization throughout the observation period. 52% were metastatic in the ten past years versus 63 %. Colorectal mortality was higher during 2010 (38%) versus (16 %) in 2020.The median overall survival was 23 months versus 32 months in the latest years. Our study showed an increase in median survival with a reduction in mortality over the past 10 years. Important progress has been observed in the treatment of metastatic colorectal cancer in recent years.

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