Evaluating laparoscopic ovarian drilling effects on anti-mullerian hormone levels in polycystic ovarian syndrome: implications for oncological considerations in radiotherapy

Abstract

Author(s): Enas Jaleel ALobaidy, Myasar Jasim Mohammed, Shaymaa Kanaan Mansoor

Laparoscopic Ovarian Drilling (LOD) diminishes ovarian androgen-producing tissue and decreases minor transformation to estrogens. This study aims to measure the level of Anti-Mullerian Hormone (AMH) before and after laparoscopic surgery among Women with polycystic ovarian syndrome PCOS. Thirty-five PCOS patients underwent LOD after a history of none response to medication and failed to conceive. The serum values of the AMH, testosterone, Luteinizing Hormone (LH), and the number of follicles has been assessed before and after surgery. The average total of AMH serum values was 7.2 ng/ml ± 3.5 ng/ml before the operation and 6.1 ng/ ml ± 3.2 ng/ml, 7.7 ng/ml ± 4.5 ng/ml, and 6.4 ng/ml ± 3.3 ng/ml one week, three weeks, and four months subsequently later. The mean serum values of LH were 12.6 IU ± 5.7 IU (p=0.87) before the operation and 12.7 ± 11.1 IU four months later. The mean testosterone hormone levels were 0.9 ng/ml ± 0.7 ng/ml, before and 0.7 ng/ml ± 0.8 ng/ml (p=0.86) after surgery. The reproductive rate was 26.7% per year. Laparoscopic ovarian drilling couldn't alliterate serum AMH, testosterone, and LH in infertile PCOS women, therefore has no opposing effect on the ovarian reserve.

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