Evaluation of the clinical conditions of patients with therapeutic cardiac angiography and In-stent restenosis risk factors for in cancer patients

Abstract

Author(s): Wallaa Luay Alfalluji, Ali Kadhim Radhi, Abbas AbdulWahhab Jumaah Al-Salihi

Background: In-Stent Restenosis (ISR) is a long-term complication of coronary artery intervention, which represents>50% re-narrowing of the artery within a period from 2 to 6 months from initial intervention. Aim: This study aims to evaluation of the clinical conditions of patients with therapeutic cardiac angiography and In-stent restenosis risk factors for in cancer patients. Material and Methods: This study was implemented. From January 2021 to October 2022, 92 patients with ISR were studied retrospectively, and their clinical and angiographic findings were analyzed. Fifty patients were taken as a controlled group. Factors and variables affecting ISR were demonstrated. Results and discussion: Seventy-three percent of the patients underwent elective Percutaneous Coronary Intervention (PCI), while Adhoc PCI was done to 27.17% of the patients. 93% of the patients underwent Predilutions prior to stent deployment. Residual stenosis was found to be 18.44 ± 6.76, and dissection as complications were occurred in 63.04% of the patients. Clinical presentation of the patients with ISR, in the form of chest pain, which was the most common presenting features, HF and positive Exercise Tolerance Test (ETT) represent 34 and 33%, respectively. Fifty-two percent of the ISRs were focal, 30.43% were diffuse, 10 percent were proliferative, and total occlusion represent 0.65%. Many factors like diabetes, ACS, and others related to the lesion characteristics and procedural aspects significantly predictive of restenosis were identified. Conclusion: Factors predictive of ISR are many and deserved to be addressed and modified.

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