Exploring the potential link between oral cancer infections and extra-oral factors in the context of cancer-related halitosis

Abstract

Author(s): Amna Kahtan Khalaf, Susan F.K. Al-Sudani

Research has been conducted to explore the link between oral diseases and numerous exogenous aspects that cause it to enhance bad breath. Oral diseases that cause bad breath consist of oral infections, poor oral hygiene, several foodstuffs, and basic medical conditions. Some of the prevalent oral diseases are periodontitis and gingivitis because they create bad breath resulting from overgrowth of microorganisms in the oral cavity.

Apart from the infection in the mouth, halitosis is also triggered by extra oral such as respiratory and gastrointestinal ailments and drugs; all these factors lead to the development of volatile Sulphur compounds as well as other odorizing molecules, which are subsequently spread through the blood and exhaled through the lungs.

In addition to situations mentioned above, extra oral factors, for example, respiratory and GI conditions and particular medicines, can cause the production of VSCs as well as additional odorous compounds. The bloodstream serves as a vehicle for these substances, and then the lungs expel them.

In general, the connection between oral illness and external factors that contribute to foul breath is intricate. A comprehensive approach to managing bad breath may involve addressing both oral and extra oral factors and addressing any underlying medical conditions.

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