Markery i modulatory angiogenezy w raku jajnika – czy można je wykorzystać praktycznie?

Abstract

Author(s): Wieslawa Bednarek, Alicja Ćwiklińska, Maria Mazurkiewicz

Select markers and modulators of angiogenesis are acknowledged prognostic factors in ovarian cancer patient. Conjointly with well-known factors such as: the age of the patient at the time of diagnosis, the degree of clinical advancement of the disease, the postoperative size of the tumor, the effusion in the peritoneal cavity, and the concentration of the CIRCA 125 antigen can all be used to formulate prognoses concerning the time of survival in about 75% cases. This work attempts to answer the question whether it is possible to practically utilize the markers and modulators of angiogenesis in their role as prognostic factors in forecasting 3 and 5-year survival times in ovarian cancer patients? A transformation of the results of a statistical analysis and construction of a nomograph is a quick and simple method to use at the patient’s bedside.

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