Nowe populacje limfocytów T pomocniczych i ich udzial w procesach rozwoju nowotworów

Abstract

Author(s): Iwona Hus, Elżbieta Staroslawska, Joanna Goned-Sebastianka, Jacek Roliński

T helper cells play an important role in the regulation of many processes of acquired immunity, including antitumor immunity. In addition to two previously known populations of Th1 and Th2 cells, an important role in the development of cancer diseases is attributed to recently described populations of T regulatory cells and Th17 cells. It is believed that regulatory T cells are essential in the induction of tolerance to the tumor, whereas the effect of Th17 cells on tumor development seems to be more divergent depending on the type of cancer and its clinical stage.

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