Orbital metastasis of nasopharyngeal carcinoma: case report and review of literature

Abstract

Author(s): Kaoutar Soussy*, Mohamed Ait Erraisse, Yahya Charifi, Zenab Alami, Meryem Boubbou and Touria Bouhafa

Orbit is an unseal site part for metastasis, especially for nasopharyngeal carcinoma. A 47-years-old man presented a right exophthalmia two years after treatment for locally advanced Nasopharyngeal Carcinoma. He was diagnosed with orbital metastasis of NPC. Loco regional assessment in the CT and MRI showed voluminous tissue process, in the right superior-external palpebral border, well limited, intensely and heterogeneously enhanced tissue hyper signal, measuring approximately (60 × 64 × 56) mm. After refusing radiotherapy, treatment was based on palliative chemotherapy with a good response initially and then a pejorative evolution of the disease. Orbital metastases of NPC are rare; considering the radio-sensitivity of the NPC, more conformal EBRT (VMAT) or Particle therapy (Protons, Carbon-ion) is required

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