Serological evaluation of IgA and IgE antibodies in asthmatic patients in Diyala governorate: Implications for oncology patients

Abstract

Author(s): Olaa Moyad Ali, Manar Ibrahim Hasan, Amal Roshdi Ahmed

The current study was designed for the serological evaluation of IgA, IgE antibodies using ELISA on a group of patients with asthma who attended the Consultation Clinic for Respiratory Diseases and Tuberculosis and the healthy in Diyala Governorate for the period from October 2020 to March 2021, where the findings of the present study revealed a significant increase in the incidence of asthma In the mean age (43.16 ± 2.14) years, when compared with the healthy group (38.35 ± 2.22) years. The results of the current study showed a significant increase in the percentage of females with asthma by (59.4%) compared to males at (40.6%). While the results of the current study showed a significant increase (P <0.008) in the level of IgA in the blood in the group of patients with asthma (24.14) IU/ml and when compared with the healthy group (22.82 IU/ml). The results of the current study also showed a significant increase (P <0.004) in the level of IgE in the blood in the group of patients with asthma (82.60) IU/ml and when compared with the healthy group IU/ml (77.98). Through these results, the current study concluded that immune factors, especially complement proteins and immunoglobulin, have a role in the mechanism of asthma disease, as they showed a close relationship in the occurrence and severity of the disease.

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