The efficiency index in relation with essential plan parameter in gamma knife stereotactic radiosurgery for arteriovenous malformation treatment plans

Abstract

Author(s): Arkan M Mhal*, Nadiya Y Mohammed and Moneer K Farage

High conformity and steep dosage gradient from the target's perimeter to healthy tissue are characteristics of SRS. Clinical trials have proven the relevance of these parameters by showing simple symptom issues. The danger of clinical radio toxicity rises over a particular amount of exposure. Therefore, radio surgical treatment protocols should restrict exposure to healthy tissue while optimizing dosage to the target volume. Numerous measures have been developed to evaluate the effectiveness of radio surgical strategy; however, they are all flawed. A fresh measure, the efficiency index (50%), based on the notion of calculating integral dosages, and is offered to address the constraints of the already used metrics.

Methods: we calculate the efficiency index value (?50%) by Divide the integral dose (mean dose X volume) for the Treatment Area (TV) by the integral dose for 50% of the isodose volume (PIV50%). The distinct Dose-Volume Histograms (DVHs) for the TV and PIV50% may be utilized to get the efficiency index value.

The result of the efficiency index ?50% value is the fraction of energy that is delivered successfully into the target within the PIV50%. Theoretically, this value is 0 to 1, with 1 being the ideal value.

Results: The value of ?50% for the 30 clinical SRS plans ranged from 43% to 84% with a mean value of 64%. This study also showed that the strong relationship between the efficiency index and essential parameters for evaluating the treatment plan in the treat of arteriovenous malformations

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