The evaluation of tumour volume and radiological features in patients with meningioma treated by multi-session, single session and hypo fractionation gamma knife radiosurgery

Abstract

Author(s): Rasha Tahseen Ibrahim*, Rasha Sabeeh Ahmed and Yasir Muhammed Hassan

Background: The Gamma Knife (GK) radiosurgery is a successful treatment option for brain tumours and functional disorders such as meningioma. The objective of this study aimed to assess better plan treatment such as multisession and hypo fractionation and single session stereotactic radiosurgery.

Patient and Methods: Fifty-Two patients with meningioma brain tumours were treated in the gamma knife centre of Al-Taj Hospital in Baghdad. An oncologist or neurosurgeon diagnoses sent patients for gamma knife therapy. Each patient's brain is examined utilizing CT and MRI to evaluate tumour features better. The neurosurgeon suggested the dose dependent upon the tumour volume and position.

Result: All patients with meningioma showing great response and improvement in the tumour size. In multisession the tumour volume disappeared in 5 patients and decreased in 13 patients. As for the hypo fractionation, it disappears in 1 patient and decreased in 7 patients. In single session the tumour volume disappears in 2 patients and decreased in 22 patients and increased in 2 patients.

Conclusion: Our Finding indicates that multisession (GKR) is a low-morbidity treatment option that is safe, effective, and well tolerated for these big lesions.

• The multisession gamma knife radiosurgery is effective in control of tumour growth of these large lesions in meningioma.
• The hypo fractionated stereotactic Radiosurgery is safe and well tolerated with acceptable rate of radiation induced complications. With frameless techniques of ICON mode of gamma knife, SRS will be more feasible and comfortable.

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