The prevalence of HSV1 expression in Iraqi patients with Colorectal cancer

Abstract

Author(s): Basim Mohammed Khashman*, Hujaz Ismail Abdulrazzaq Alqirb and Heba F. Hassan

Background: Colorectal Cancer (CRC) is one of the most serious
health problems and Herpes viridae may hasten the progression of
colon cancer.
Aim: The purpose of conducting this research is to investigate the
existence of Herpes Simplex Virus (HSV1) infection in samples of
Colorectal Cancer (CRC) compared with normal tissue.
Material and Methods: 40 samples of tissues (30 patients ) with CRC,
and (10 samples) of normal tissue (without cancer) were obtained, for
immunohistochemically analysis of Herpes Simplex Virus (HSV1)
expression
Results: The results showed no significant data to justify the link
between both Herpes Simplex Virus (HSV1) and human colorectal
cancer. Despite of presence of Herpes Simplex Virus (HSV1) found in
six samples (20 %) by using Immunohistochemistry staining. There is
a low relationship between the presence of HSV1 and CRC. The
results supported a histopathological diagnostic element; it could
possibly be seen in the diagnosis and treatment of CRC.

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