The prevalence of lymph proliferative disorders in a group of Iraqi patients and its relation to blood indices parameters

Abstract

Author(s): Enass Abdul Kareem Dagher Al-Saadi* and Marwa Ali Abdulnabi

Abstract: Lymphoproliferative Disorders (LPDs) are a group of neoplasms affecting various cells within lymphoid system. Each type has different treatment and prognosis. Objective: To measure the prevalence of LPDs in a sample of Iraqi patients delineating its specific phenotypes in terms of their prevalence and male to female ratio. Design: Cross sectional study. Materials and methods: Cross sectional study that is done at National Centre of Haematology from November 2019 till March 2020 on 64 patients who were diagnosed to have one subtype of MPDs. Blood samples were taken from them and analysed to get complete blood count using automated electronic counter (Haematology auto-analyser-BECKMAN COULTER, ACT. 5 diff. USA). Blood film, Bone marrow aspirate and biopsy were analysed for each patient. Data were presented in frequencies and percentages and analysed using Chi-Square, student T test and ANOVA test when applicable using Graph pad 8 software and p=0.05 as significance level. Results: CLL is the most common pathologic type that accounts for (42.2%), followed by follicular lymphoma (23.4%), mantle cell lymphoma (10.94%), B-cell lymphoblastic leukaemia/lymphoma (9.38%), lymphoma (4.69%), Splenic Marginal Zone Lymphoma (4.69%) and T-cell NHL (4.69%). LPDs were more prevalent in males apart from Hodgkin’s lymphoma. Discussion and Conclusion: LPDs is a group of many lymphoid neoplasms that vary in their prevalence. The prevalence observed in our population is greatly different form the cited literature. This could be explained by the low number of patients in our sample.

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