Alaa I Amer

Publications

• Research Article   
  Keap1, Estrogen and Progesterone Receptors as Prognostic Factors in Endometrial Carcinoma: An Immunohistochemical study
  Author(s): Aya S Amer, Heba A Mashhour, Hanan A AlShenawy, Hassan Tahseen Sheir and Alaa I Amer*
  
  Background: Endometrial carcinoma is the most common malignancy of the female reproductive system and represents the sixth most prevalent malignant tumour all over the world. The purpose of this study was to evaluate the expression of Keap1, estrogen and progesterone receptors immunoreactivities in a spectrum of endometrial carcinoma cases and correlate Keap1, estrogen and progesterone receptors immunohistochemistry expression in the endometrial carcinoma with available clinicopathological parameters. Paraffin blocks from 70 cases of endometrial carcinoma, 52 cases of endometrioid type and 18 cases of non-endometrioid type were subjected to H&E staining and immunohistochemical staining by Keap1, estrogen and progesterone receptors. Results: Keap1 was expressed as cytoplasmic staining mainly and its expression was related to worse prognosis as it was statistically significant assoc.. Read More»
  

  Abstract PDF