Asaad Abdulameer Khalaf
Basrah Center of Oncology and Haematology, Basrah Health Directorate, Ministry of Health/Environment, IraqPublications
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Research Article
Treatment-free remission in Chronic Myeloid Leukemia (CML): experience of basra hematology center
Author(s): Ali Khazaal Jumaa*, Asaad Abdulameer Khalaf, Hasson Mahdi Hasson, Qutaiba Muslim Dawood and Zaynab Raad Qasim
Improved survival rates in Chronic Myeloid Leukaemia (CML) lead to increasing prevalence of the disease, increasing cost and burden on health care systems. The current study aimed to assess the outcome of CML patients that maintained a durable molecular response, after TKI stopping in Iraq. The study enrolled 18 patients with CML who were treated for more than 5 years with Tyrosine Kinase Inhibitors (TKIs) and got a Major Molecular Response (MMR) for 2 years. All patients were subjected to close follow-up after stopping TKI with PCR every 3 months to monitor molecular response. Median age of 45-year, median duration of disease before stopping TKI was the 93-month and median duration of MMR was 37-month. During a median duration of 24 months of follow-up after TKI stopping, 13 patients (72%) succeeded to maintain MMR, while 5 patients (28%) did not. The molecular relapse occurred durin.. Read More»
Editors List
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Ahmed Hussien Alshewered
University of Basrah College of Medicine, Iraq
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Sudhakar Tummala
Department of Electronics and Communication Engineering SRM University – AP, Andhra Pradesh
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Alphonse Laya
Supervisor of Biochemistry Lab and PhD. students of Faculty of Science, Department of Chemistry and Department of Chemis
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Fava Maria Giovanna
- Manuprasad Avaronnan
Onkologia i Radioterapia peer review process verified at publons
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