Gent Sopa
Department of Obstetrics and Gynaecology, Faculty of Medicine, University of Pristine, Pristine, KosovoPublications
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Book Review
Expression of PD/PD-L1 as a prognostic biomarker in ovarian serous carcinoma carcinoma - A literature review
Author(s): Astrit M. Gashi, Brikene Elshani*, Hajrullah Latifi, Gent Sopa, Jakup Ismajli and Arianit Sherifi
Ovarian cancer has the highest mortality rate of any gynecologic malignancy other. Even after optimal treatment, the prognosis remains poor. To date, no biomarker can predict the individual outcome of a patient with this disease. Two decades of studies have investigated the prognostic value of PD-1/PD-L1 in high-grade serous ovarian carcinoma; many issues remain unclear, controversial, inconsistent, and often contradictory. PD-L1 is an important immunoregulatory factor and, as a receptor for PD-1, plays an important role in inhibiting the immune response to cancer cells, thus negatively regulating T cell functions. The level of expression in PD-L1 is related to the patient's survival rate and prognosis in various types of cancers, including ovarian cancer, particularly serous ovarian carcinoma. The level of expression in PD-L1 increases the potency of tumour immunogenicity, increa.. Read More»
Editors List
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Ahmed Hussien Alshewered
University of Basrah College of Medicine, Iraq
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Sudhakar Tummala
Department of Electronics and Communication Engineering SRM University – AP, Andhra Pradesh
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Alphonse Laya
Supervisor of Biochemistry Lab and PhD. students of Faculty of Science, Department of Chemistry and Department of Chemis
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Fava Maria Giovanna
- Manuprasad Avaronnan
Onkologia i Radioterapia peer review process verified at publons
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