Lamia F. Abu-Marzoq

Publications

• Research Article   
  The anticancer effects a new benzimidazole on HCC1937 breast cancer cell line
  Author(s): Lamia F. Abu-Marzoq*
  
  Background: The lack of selectivity of the present medications and the decreased sensitivity to tumor therapies are the two main barriers to the treatment of solid tumors. This study's goal was to evaluate the anticancer activity of newly created benzimidazole medication compounds against the HCC1937 cell line, which has been the subject of numerous studies suggesting benzimidazole compounds and their derivatives as prospective targeted treatments and EGFR inhibitors. Methods: Clonogenic survival assay used to inhibit the colony formation, A trypan blue assay was used to determine BA586's capacity to cause cell death in the HCC1937 cell line. MTT was used to assess the cytotoxicity of BA586 on HCC1937 triple-negative cells. To evaluate the BA586's capacity to prevent migration, a scratch motility assay was employed. The western blotting technique was performed to.. Read More»
  

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