Makarewicz Roman

The Chair and Clinic of Oncology and Brachytherapy, Nicolaus Copernicus University in Torun, Ludwik Rydygier Collegium Medicum in Bydgoszcz, Poland

Publications

• Research Article   
  Evaluation of selected proinflammatory factors, angiogenesis and lymphangiogenesis as potential markers of early tumor recurrence in patients undergoing surgical treatment for prostate cancer
  Author(s): Kamecki Krzysztof, Biedka Marta*, Makarewicz Roman, Goralewska Alina and Jolanta Mrochem-Kwarciak
  
  Introduction: Up to a half of patients after radical prostatectomy due to prostate cancer have biochemical recurrence, i.e., PSA concentrations >0.2 ng/ml. In most patients, biochemical recurrence does not significantly affect survival and quality of life; however, in about one third of patients, biochemical recurrence precedes a clinically relevant recurrence of prostate cancer. Usually, based on the current criteria of biochemical recurrence, prostate cancer recurrence is diagnosed several months after surgery. This delays adjuvant treatment and worsens treatment outcomes. This study aimed to check whether preoperative concentrations of markers of angiogenesis, lymphoangiogenesis, and extracellular matrix degradation could predict biochemical recurrence of prostate cancer after radical prostatectomy. Materials and methods: The study included 82 patients who underwent radical pros.. Read More»
  

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