Manjula M. V.

Publications

• Research Article   
  Incurable head and neck cancers: will quad shot be an optimum shot?
  Author(s): Manjula M. V., Pawar Y.S.*, Shamsundar S. D., Shirali Agarwal, Gowtham Raj, Thejaswini B., Nanda R., Aradhana Katke and Ajay GV
  
  Objective: The primary objective was to estimate palliation of symptoms and tumour response. The secondary objective was to evaluate the toxicity and outcome in three palliative hypo fractionated regimens. i.e. conventional, Quad shot schedule, Quad shot with concurrent chemotherapy. Methods: The patients were randomly divided into 3 arms. Arm1 received conventional schedule -30 Gy in 10 fractions, one fraction per day for a period of 2 weeks; Arm 2 patients received quad shot schedule - 14.4 Gy in 4 fractions, 2fractions per day, 6 hours apart, a total of 2 sessions; Arm 3 patients received quad shot schedule-14.4 Gy in 4 fractions, 1 fraction per day with chemotherapy-Carboplatin (AUC2) on day 1 of each cycle, total of 2 sessions. patients were assessed 4 weeks post 1 session, those with progressive disease or grade 3/4 toxicity patients were managed with best supportive care. Patie.. Read More»
  

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