Zainab N. Al-Abady
Department of Chemistry, College of Sciences, University of Al-Qadisiyah, Diwaniyah, IraqPublications
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Research Article
MicroRNA-223 and oxidant-antioxidant status in leukemia patients
Author(s): Zainab M. Hillel and Zainab N. Al-Abady*
The aim of the study was to elucidate miRNA-223 expression in patients with acute myeloid leukemia, acute lymphocytic leukemia and chronic myeloid leukemia and regulate miRNA-223 expression in oxidative stress based on current research. 40 patients with Acute Lymphoblastic Leukemia (ALL), 40 patients with acute myeloid leukemia (AML), 30 patients with Chronic Myeloid Leukemia (CML) and 40 healthy subjects served as controls. A colorimetric method was used to measure Catalase (CAT) and Malondialdehyde (MDA) activity. The serum concentrations of Heme Oxygenase 1 (HMOX1) were measured by Enzyme Immunoassay (ELISA). A quantitative polymerase chain reaction was used to determine serum miRNA-223 expression. It was found that CAT activity was significantly reduced in the patient groups compared to the control group (p<0.05), but MDA and HMOX1 concentrations were significantly higher in th.. Read More»
Editors List
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Prof. Elhadi Miskeen
Obstetrics and Gynaecology Faculty of Medicine, University of Bisha, Saudi Arabia
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Ahmed Hussien Alshewered
University of Basrah College of Medicine, Iraq
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Sudhakar Tummala
Department of Electronics and Communication Engineering SRM University – AP, Andhra Pradesh
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Alphonse Laya
Supervisor of Biochemistry Lab and PhD. students of Faculty of Science, Department of Chemistry and Department of Chemis
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Fava Maria Giovanna
Google Scholar citation report
Citations : 518
Onkologia i Radioterapia received 518 citations as per Google Scholar report
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